Prague Hotels and Apartments Prices in Prague are always subject to frequent changes, and so are the places where you can accommodate yourselves (except for posh and expensive hotels).
The Hotel Josef at 20 Rybna in Josefov is in the former Jewish quarter of Prague’s Old Town. The hotel, Jiricna’s largest new building, is off a tiny square, an urban clearing formed by the junction of three streets. The square is dominated by a decorative nineteenth-century police station which flanks the hotel’s south side. The hotel is two buildings (colour-coded pink at the front, orange at the back) separated by an internal courtyard and linked by a glass corridor. A practical response to a deep and irregular site, which slopes from west to east, the arrangement allowed an underground car park and brought natural light into the center of the plan. Public areas flow seamlessly around the courtyard. Giving onto the garden through along glazed wall is the breakfast room.
Moevenpick Praha is a large and well appointed hotel, with pretty much all you need for a tourist, or, from appearances, business stay. The location is fairly far from central, in Smichov.
U Prince is a very pretty place right on old town square; the restaurant is very very touristy, jazz in the evening, nice roof top restaurant as well. I did experience that myself in the restaurants as well. Check Grand Hotel Praha, we have had some very positive comments in this forum and it has the same location.